One study showed that periods of ASMR tingling were associated with increased activation in brain regions involved in emotion, empathy, and affiliative behaviors.

Other studies show that people with ASMR have less distinct and more blended neural networks, suggesting that ASMR could happen because of a reduced ability to suppress emotional responses that we obtain from our senses.

Research suggests that people who experience ASMR have a larger tendency to have more immersive or absorbing experiences.

People with ASMR score higher on 'openness to experience,' reflecting imagination, intellectual curiosity, and appreciation of art and beauty. People with ASMR are also more empathetic when looking at compassion and concern for others.

People with ASMR show significant reductions in their heart rates when watching ASMR videos.

These stress reductions were similar to those experienced during mindfulness and music therapy. But research is not clear whether ASMR can and should be used as an effective form of therapy.