What are the ways to defeat it? (Pt. 2) - Deepstash
What are the ways to defeat it? (Pt. 2)

What are the ways to defeat it? (Pt. 2)

Zapping Bacteria:

It disrupts the membrane of bacterial cells with PL0206, a small protein that is attracted to the negatively charged environment inside a biofilm.

This method has been carried on Phase 1 clinical trial with 14 patients with prosthetic joint infections, where interim data looks promising.

Tearing it down:

It loosens two universal components of biofilms, known as DNA-B-II. Loosening the DNA scaffolding of the biofilms would cause a collapse of the structure.

Tested on two dozen bacterial species, no biofilms survived the disappearance of DNABII.

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