Oxygen was the atomic weight standard for the other elements until 1961 when it was replaced by carbon 12.
Oxygen made a good choice for the standard before much was known about isotopes because although there are 3 natural isotopes of oxygen, most of it is oxygen-16. This is why the atomic weight of oxygen (15.9994) is so close to 16. About 99.76% of oxygen is oxygen-16.
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