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To Understand How, We Need A Lesson On Human Sex Differentiation
- Humans have an XY sex-determination system.
- The Y chromosome carries the SRY gene (also known as TDF) which determines testicular formation.
- The testes formed in the presence of the SRY gene secretes hormones (dihydro-testosterone).
- Hormonal changes induce development of external & internal sex organs (penis, scrotum & wolffian ducts).
- The absence of SRY gene leads to the development of different internal and external organs (vulva, uterus, fallopian tubes).
This process of sex organ development through chromosomal & hormonal mechanisms is known as sex differentiation.
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So why does it happen?
In the 1970s, Dr Julianne Imperato-McGinley, discovered that they have a genetic condition that causes a deficiency in an enzyme called 5-alpha-reductase, which converts testosterone into dihydro-testosterone.
Thus, male external & internal...
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The discovery of a small community in the Dominican Republic, where some males are born looking like girls and only grow penises at puberty, has led to the development of a blockbuster drug that has helped millions of people
MICHAEL MOSLEY
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How Did The Guevedocs Helped Develop A Drug That Helps Millions?
Another thing that Imperato-McGinley discovered was that the Guevedoces tend to have small prostates.
This observation led to the development of the best-selling drug, finasteride, which blocks the action of ...
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79 reads
What Do These Findings Imply On Human Sexuality?
A final interesting observation that Imperato-McGinley made was that these boys, despite being brought up as girls, almost all showed strong heterosexual preferences. She concluded prenatal hormones play a bigg...
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132 reads
Biological Processes Are Never Universal
The process of sex differentiation ensures that human fetuses are born with distinct external & internal genitalia (which is used to assign their sex at birth).
However, in a small town in the Dominican Republic, a community known as the "G...
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99 reads
CURATED FROM
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Just a queer, brown, psychology undergraduate ranting about random things I come across. I organize my thoughts in little, informative chunks and try to cite my sources. #psychology #society #marxism #philosophy #leftist #LGBTQ #gay #trans #queer
More like this
Biological Processes Are Never Universal
The process of sex differentiation ensures that human fetuses are born with distinct external & internal genitalia (which is used to assign their sex at birth).
However, in a small town in the Dominican Republic, a community known as the "G...
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