As neuroscientist Rodolfo Llinás points out, all life is based on prediction. Even unicellular organisms detect changes in the environment and either embrace them (food; sex) or flee (predators).
Humans are no different. We depend on and react to environmental changes all the time:
the deer bounding across the street breaking up the monotony of a long drive; the distracted ambivalence of a scorned lover; the anxiety-creating noise of your phone's alerts.
We are primed for change.
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