Addicts, for instance, crave drugs even after years of abstinence because addictive substances hijack the dopamine system and change it permanently.

When exposed to addictive substances like cocaine, heroin, alcohol, nicotine and even sugar, neurons are releasing more dopamine, and also gro...

In 1986, a discovery was made that dopamine did not produce pleasure, but in fact, desire. While dopamine makes us want, pleasure comes from opioids and endocannabinoids ( a kind of marijuana produced in the brain), which paints pleasure on good experiences.

The reward system in our brain exists to ensure we seek out what we need. If eating nutritious food or being smiled at pleases us, we try to secure more of these stimuli. However, seeking pleasure can also result in people becoming addicted, indebted or overweight.

Something as simple as dropping your keys once will fire dopamine neurons. But, if you drop them a few more times, the neurons will get bored and stop taking notice.

The market economy has increased the dopamine-wanting system. If you can give the consumer novelty, they will continuously wa...

The closest we can come to hold on to pleasure is in music. It is a tension-and-release kind of thing that can keep you going for a long time, waxing and waning, desiring and enjoying.

Music also tends to unite us - dancing with someone is more fun than doing it alone. It's all about other ...

We cannot explain away our minds by brain mechanisms. Brain mechanisms are part of our minds.

Understanding that desire and dread, for instance, share the same brain operations, could help ease schizophrenia symptoms by restricting a particular dopamine neuron that produces fear.