Adenosine builds up the longer we are awake, creating a “sleep drive” or hunger. It binds to receptors in the brain that normally promote wakefulness. Caffeine promotes wakefulness by blocking adenosine receptors. Each person must determine how caffeine impacts them and at what times of day it is appropriate.
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The podcast discusses how to optimize one's sleep-wake cycle by controlling light exposure, timing of food and exercise, and relaxation practices. It covers the role of adenosine, circadian rhythms, cortisol, and melatonin in regulating alertness and sleepiness. Viewing bright light, ideally sunlight, during the day and avoiding it at night helps to anchor one's circadian clock and hormonal cycles for better sleep, mood, and health.
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