<ul><li>90-minute ultradian rhythms govern alertness, energy, and sleep-wake cycles during the day. Aligning demanding work or learning with peak periods in one’s personal ultradian rhythm leads to greatest productivity.</li><li>Most people experience peak alertness 3 hours after waking and in early evening. Early exercise and fasting increase daytime alertness.</li><li>Delaying caffeine for 2 hours after waking allows natural cortisol release and adenosine suppression, preventing crashes. Evening carb-rich meals increase nighttime calm and sleepiness.</li></ul>

Autonomic Arousal and Biological Rhythms

<ul><li>Highly-focused, linear alert states are optimal for learning and strategy implementation.  Low arousal states facilitate novel arrangements, the first phase of creativity.</li><li>The basal ganglia's activation of “go” and “no-go” pathways depends on arousal levels. High alertness activates “go” (pursue action) but impairs “no-go” (suppress action). Calm states allow both.</li><li>During peak alertness, silence and avoiding background inputs helps linear tasks. For low arousal, ambient noise may help. Creativity requires both generating new ideas (relaxed exploration) and implementing them (deliberate focus).</li></ul>

Learning, Focus, and Creativity

<ul><li>Know your personal ultradian rhythm, chronotype, and arousal tendencies. Align activities and environments accordingly. </li><li>Practice focused linear work during peak alertness and creative exploration in relaxed states. Balance both for optimal productivity and innovation.</li><li>Utilize biological tools to regulate arousal like light, temperature, nutrition, rest, and physical activity. They are safer and more targeted than most supplements or drugs.</li><li>Refine self-awareness to determine which techniques (visualization, meditation, etc.) work for your goals and tendencies. Don't assume one-size-fits-all. </li></ul>

Optimize Your Brain with Science-based Tools — Key Takeaways

<ul><li>A burst of alertness 1 hour before bed is normal. Use it for routine tasks, then rest. Thoughts during night awakenings are unreliable and incoherent. Utilize relaxation techniques to fall back asleep. </li><li>Non-sleep deep rest (yoga nidra, meditation) facilitates renewal, insight, and neuroplasticity when time-limited. Combine with learning for maximum benefit. </li><li>Quality and timing of sleep are as important as duration. Understand and adjust your chronotype. Light, activity, and temperature are powerful for setting circadian rhythms. Use tools to optimize sleep conditions.</li></ul>

Sleep, Rest, and Regeneration

<ul><li>Individuals vary in tendencies toward high or low arousal, “go” or “no-go”. Self-awareness and experimenting with techniques that modulate arousal levels and behavior can help determine optimal times and states for activities.</li><li>For some, visualization enhances learning and performance. For others, mind wanders easily. Try focused visualization. Look for measurable results.</li><li>Creativity requires both generating new ideas and implementing them in a coherent, logical manner. Psychedelics may facilitate the former, but not the latter.</li></ul>

Considerations

The podcast explores avenues toward optimizing one's brain through neuroplasticity. It discusses how alertness, diet, exercise, routines, and restorative practices influence learning, productivity, and well-being. Dr. Huberman describes strategies for leveraging biology to achieve one's goals by aligning activities and environments with natural rhythms.

In this episode, I describe how to access focused learning bouts, creative states, and the underlying neural circuitry involved. I frame this in the context of our daily 24-hour cycle in order to make it practical, clear and precise about timing. I review the role of fasting, meal timing and specific types of nutrients for promoting certain states of mind. I also review various other tools and biological factors that directly or indirectly gate brain function and that we can control. I answer commonly asked questions about the science of psychedelics, binaural beats, and visualization. Thank you for your interest in science! For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Thesis: https://takethesis.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Introduction (00:00:30) Sponsors: AG1, LMNT, Thesis, Momentous (00:04:53) The Daily (Learning) Routine (00:07:13) Plasticity Is NOT the Goal (00:09:26) No Obligation To Change (00:09:59) Practical Plasticity Language (00:13:37) Pillars of Neuroplasticity (00:15:16) My Daily Routine: Chronotype Management (00:17:20) Plasticity of the Wake-Sleep Circuit: Morning Light (00:19:09) Delay Caffeine! (00:21:19) Light, Black Coffee, Hydrate (00:22:57) High Alertness, Linear Tasks/Learning (00:25:12) Background Music/Noise: Yay or Nay? (00:26:52) “GO” versus “NO-GO”: The Basal Ganglia & Dopamine (00:28:37) Leveraging GO, NO-GO (00:30:08) Non-Specific Action (00:32:06) Clear, Calm, Focused: The GO, NO-GO Sweet Spot (00:33:48) When Very Alert, Work In Silence; When Tired, Include Background Noise (00:35:28) Temperaments Vary: And So Should This (00:36:01) The 3 Hour-Long Post Waking Block (00:36:20) Early Morning Exercise and GO Networks (00:38:05) Fasting, Ketogenic Diets, & Food Volume (00:39:41) Sodium/Electrolytes (00:40:57) Avoiding Hot Lunch, Food Pre-Occupation (00:42:01) Post Lunch Low/No Cognitive Load (00:42:56) Hydration, NSDR, Nap (00:44:54) Creativity Work (00:46:26) Creativity Is A Two-Part Phenomenon (00:51:15) Psychedelics (00:58:20) Afternoon Light As Insurance (01:00:26) Evening Nutrition (01:01:21) Repacking Glycogen: Hormonal Factors (01:04:11) Pre-Sleep Anxiety: Normal and Easy To Solve (01:07:08) The Power of Objective Tools (01:08:14) Visualization (01:11:34) Mini-Synthesis (01:13:31) Resetting Your Clock (01:15:55) Don’t Trust the Mind Now (01:16:59) Two, (Maybe 3) Optimization Bouts Per Day (01:18:33) Organizational Logic (01:20:22) Wim Hof Breathing, Binaural Beats, Ice Baths, Etc. (01:24:42) Variation Among People, and Dogs (01:25:49) Accurate Versus Exhaustive (01:27:57) Familiar and New Ways To Support Title Card Photo Credit: Mike Blabac Disclaimer

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In this episode, I describe how to access focused learning bouts, creative states, and the underlying neural circuitry involved. I frame this in the context of our daily 24-hour cycle in order to make it practical, clear and precise about timing. I review the role of fasting, meal timing and specific types of nutrients for promoting certain states of mind. I also review various other tools and biological factors that directly or indirectly gate brain function and that we can control. I answer commonly asked questions about the science of psychedelics, binaural beats, and visualization. Thank you for your interest in science! For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Introduction (00:00:30) Sponsors: AG1, LMNT (00:04:53) The Daily (Learning) Routine (00:07:13) Plasticity Is NOT the Goal (00:09:26) No Obligation To Change (00:09:59) Practical Plasticity Language (00:13:37) Pillars of Neuroplasticity (00:15:16) My Daily Routine: Chronotype Management (00:17:20) Plasticity of the Wake-Sleep Circuit: Morning Light (00:19:09) Delay Caffeine! (00:21:19) Light, Black Coffee, Hydrate (00:22:57) High Alertness, Linear Tasks/Learning (00:25:12) Background Music/Noise: Yay or Nay? (00:26:52) “GO” versus “NO-GO”: The Basal Ganglia & Dopamine (00:28:37) Leveraging GO, NO-GO (00:30:08) Non-Specific Action (00:32:06) Clear, Calm, Focused: The GO, NO-GO Sweet Spot (00:33:48) When Very Alert, Work In Silence; When Tired, Include Background Noise (00:35:28) Temperaments Vary: And So Should This (00:36:01) The 3 Hour-Long Post Waking Block (00:36:20) Early Morning Exercise and GO Networks (00:38:05) Fasting, Ketogenic Diets, & Food Volume (00:39:41) Sodium/Electrolytes (00:40:57) Avoiding Hot Lunch, Food Pre-Occupation (00:42:01) Post Lunch Low/No Cognitive Load (00:42:56) Hydration, NSDR, Nap (00:44:54) Creativity Work (00:46:26) Creativity Is A Two-Part Phenomenon (00:51:15) Psychedelics (00:58:20) Afternoon Light As Insurance (01:00:26) Evening Nutrition (01:01:21) Repacking Glycogen: Hormonal Factors (01:04:11) Pre-Sleep Anxiety: Normal and Easy To Solve (01:07:08) The Power of Objective Tools (01:08:14) Visualization (01:11:34) Mini-Synthesis (01:13:31) Resetting Your Clock (01:15:55) Don’t Trust the Mind Now (01:16:59) Two, (Maybe 3) Optimization Bouts Per Day (01:18:33) Organizational Logic (01:20:22) Wim Hof Breathing, Binaural Beats, Ice Baths, Etc. (01:24:42) Variation Among People, and Dogs (01:25:49) Accurate Versus Exhaustive (01:27:57) Familiar and New Ways To Support Title Card Photo Credit: Mike Blabac Disclaimer

Huberman Lab discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.