Primary Cause of Depression - Deepstash

Primary Cause of Depression

For decades, we thought that the primary pathology, the primary cause of depression was some abnormality in these neuro-transmitters, specifically serotonin or norepinephrine.

However, norepinephrine and serotonin did not seem to be able to account for the symptoms of depression in people who had major depression.

Instead, the chemical messengers between the nerve cells in the higher centers of the brain involved in regulating mood and emotion, which include glutamate and GABA, were possibilities as alternative causes for the symptoms of depression.

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irza_fi

interested in psychology, philosophy, and literary📚 | INTP-T & nyctophile | welcome to Irza Fidah's place of safe haven~! hope you enjoy my curations and stashes^^.

For many people, depression turns out to be one of the most disabling illnesses that we have in society. Despite the treatments that we have available, many people are not responding that well. It's a disorder that can be very disabling in society. It's also a disorder that has medical consequences. By understand the neurobiology of depression we hope to be able more to find the right treatment for the patient suffering from this disease.

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Neurotransmitters

Neurotransmitters

Neurotransmitters are chemical messengers in the brain. The nerve cells of the brain use neurotransmitters to communicate with each other. The messages they send are believed to play a role in mood regulation.

The three neurotransmitters implicated in depression are:

  • Dopamine

Norepinephrine

Norepinephrine

Norepinephrine is both a neurotransmitter and a hormone. It plays a role in the "fight or flight response" along with adrenaline. It helps send messages from one nerve cell to the next.

Changes in norepinephrine levels do not affect mood in every person. Researchers now understand that hav...

Causes of Low Neurotransmitter Levels

Causes of Low Neurotransmitter Levels

Research has indicated several potential causes for the low levels of serotonin, norepinephrine, or dopamine:

  • Molecules that help make neurotransmitters are in short supply
  • Not enough receptor sites to receive the neurotransmitter
  • Presynaptic cells are taking the ne...

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