You take a group of group of young, healthy people, who presumably have lots of anabolic capacity. You put them in a cast for 1 week, and you immediately demonstrate, upon removing the cast, that the leg that has been immobile for a week is 35% less responsive to protein assimilation than the other leg. That’s an anabolic resistance factor of 35%, that is far greater than what you see in an aged individual.
So, with 1 week of inactivity, you (can) make a young leg or young muscle respond completely like a senescent muscle.
LUC VAN LOON
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We (can) become more of what we eat or less of what we eat. | Age within an individual can simply be a proxy for activity. | Muscle itself doesn’t seem to get that old.
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And now the fun thing: you take an aged individual, who might have 20% or 30 % less anabolic response to protein than a young person. If you exercise them, you can bring them up to the same level as a young person.
These two factors s...
LUC VAN LOON
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