Embracing failure
The alternative to running out of steam is to fail better. Skeptics may wonder how to write a grant proposal where you promise to "fail better," or getting a job with a research strategy that lays out your program for failing better.
Yet, that is the right way to proceed. If you are reviewing a grant, you should be interested in how it will fail - usefully. Ask a candidate for a faculty position who has just presented his or her five-year research plan, what is the percentage of this that is likely to fail, otherwise it may be to simplistic. We often don't know what we don't know. The unknown will only be revealed by failures.
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