Pain signal activates many regions of the brain like the brainstem, thalamus and multiple cortex areas. The brain surprisingly can suppress, amplify, reappraise and attenuate the incoming pain signal, coating it with emotions to turn up the volume.
The brain can talk to the spinal cord and suppress pain, like a brake, at least temporarily. This system is called a descending pain modulatory system, and results in a sort of placebo effect.
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When we feel acute pain, we act according to our past experience, preset responses and other environmental and social factors, taking the help of some natural powers of our brain, we can even temporarily block our pain. Pain drives us towards action, prompting a fight or flight response.
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