What's motivation neurologically?

For motivation, there are multiple brain regions involved, but one in particular is the reward centre of the brain. It consists of two key areas: one called VTA (ventral tegmental area) and the other called nucleus accumbens (or NACC).

During pleasant activities, the VTA secretes a chemical called dopamine. Dopamine is called the molecule of pleasure – anything that feels enjoyable to us, it feels that way because of dopamine.

And different activities secrete different levels of dopamine. And the things which are enjoyable, such as our favourite food, or time with our loved ones, they secrete high levels of dopamine.

Interestingly, there is some research showing that actually in order to secrete more dopamine, we need unpredicted rewards.