Proteins are made of long ribbons of amino acids, which twist themselves up into complicated knots. Knowing the shape of a protein’s knot can reveal what that protein does, which is crucial for understanding how diseases work and developing new drugs—or identifying organisms that can help tackle pollution and climate change. Figuring out a protein’s shape takes weeks or months in the lab. AlphaFold can predict shapes to the nearest atom in a day or two.
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