The role of sirtuins when it comes to ageing in the brain - Deepstash

The role of sirtuins when it comes to ageing in the brain

While your body clock is ticking away, the loops and bundles of the DNA are getting messed up. When a cell is overstressed and damaged, the sirtuins have two jobs:

  1. They have to make bundles of DNA and ensure the cell has its identity. When the chromosomes break or you crush a cell, the sirtuins rush in to help repair the broken DNA.
  2. Sirtuins then have to reestablish that structure. They can put back 99.9% of those structures to how they were. But that .1% never goes back and accumulates over time. That is called ageing. 

To mitigate that, we need to upregulate the sirtuins through NAD boosters.

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