- In 1994, one trial followed the lives of 29,133 Finish people in their 50s who all smoked. Some were given beta-carotene supplements. The group that supplemented with Beta-carotene had a 16% increase in lung cancer.
- Another study shows a breast cancer increase of 20% for postmenopausal women who supplemented with folic acid.
- One study with 100 heavy smokers had a 28% increase in lung cancer after just four years of beta-carotene and vitamin A supplementation.
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