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Humans, like many other species , regulate protein intake more strongly than any other dietary component and so if protein is diluted there is a compensatory increase in food intake.
The hypothesis proposes that the dilution of protein in modern-day diets by fat and carbohydrate-rich processed foods is driving increased energy intake as the body seeks to satisfy its natural protein drive — eating unnecessary calories until it does so.
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With the World Health Organization (WHO) declaring obesity as the largest health threat facing humanity, the authors of a new paper by the Royal Society argue that there needs to be a focus on integrative approaches that examine how various contributors interact in obesity, rather than looking at them as competing explanations. This will also help researchers and policymakers understand how to move the field forward and which causes might be most relevant to tackling the rising obesity epidemic.
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The authors conclude: “… it is only through situating specific nutrients and biological factors within their broader context that we can hope to identify sustainable intervention points for slowing and reversing the incidence of obesity and associated complications.”
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The “protein leverage” hypothesis suggests that humans consume more food when dietary protein is diluted, especially with modern processed diets.
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