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One study asked healthy participants to eat pizza until they felt full. Then on a separate day to eat pizza until they couldn't anymore. They ate twice as much as on the first take, suggesting that when you feel full, you're probably only half full.
Blood samples were also taken at regular intervals to see how the body was coping. Despite eating twice as much food, there was only a small increase in blood sugar and blood fat levels.
Healthy humans rely on the body's ability to work harder in times of need.
However, when we repeatedly eat too many calories at each meal, metabolic syndrome - a combination of high blood pressure, diabetes, and obesity - will result. Over time, the body will become unable to react to these situations.
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