- 1628 William Harvey publishes An Anatomical Study of the Motion of the Heart and of the Blood in Animals which forms the basis for future research on blood vessels, arteries and the heart
- 1656 Sir Christopher Wren experiments with canine blood transfusions
- 1670 Anton van Leeuwenhoek discovers blood cells
- 1683 Anton van Leeuwenhoek observes bacteria
- 1701 Giacomo Pylarini gives the first smallpox inoculations
- 1747 James Lind publishes his Treatise of the Scurvy stating that citrus fruits prevent scurvy
- 1763 Claudius Aymand performs the first successful appendectomy
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