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Modulating Dopamine Levels (1)

  • The key is to not expect or chase high levels of dopamine when we participate in certain activities.
  • Intermittent schedules can keep you motivated and engaged: make sure dopamine peaks don’t occur too often and vary how much dopamine you experience with that activity.
  • Whatever activities you’d like to continue over time, pay attention to how much dopamine you get and modulate accordingly

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MORE IDEAS ON THIS

ANDREW HUBERMAN

Don't spike dopamine prior to engaging in effrort.

Don't spike dopamine after engaging in effort.

LEARN TO SPIKE DOPAMINE FROM EFFORT ITSELF.

ANDREW HUBERMAN

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Your Dopamine History Really Matters

How much dopamine you experience from something depends on your baseline level of dopamine when you arrive there and your previous dopamine peaks.

Thus, when you repeatedly engage in something you enjoy your threshold for enjoyment goes up and up and up.

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ANDREW HUBERMAN

After a peak, the level of dopamine drops below baseline. The extent to which it drops is proportional to how high the peak was.

This explains why doing the same behaviours will not produce the same level of joy.

ANDREW HUBERMAN

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Why is dopamine important?

Why is dopamine important?

Dopamine is the primary determinant behind how excited we are, how motivated we are, and how ready we are to push through things to get what we want

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Dopamine release

  • There is a baseline level of dopamine circulating in your brain and body all the time (important for how you feel generally) - tonic release of dopamine
  • You can experience peaks dopamine above baseline - phasic release of dopamine

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ANDREW HUBERMAN

Telling yourself that exercise (fasting, etc) is good for your will reinforce the extent to which it is good for you at a chemical level.

ANDREW HUBERMAN

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Other dopamine facts

  • Dopamine is a neuromodulator – influences the communication of many neurons at once.
  • There are 2 main neutral circuits used by dopamine to exert effects: (1) mesocortical limbic pathway – responsible for reward, motivation, craving; (2) nigrostriatal pathway

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ANDREW HUBERMAN

How satisfying an experience is depends on the height of the peak relative to the baseline. Increasing dopamine will make you motivated but it will be short lived.

ANDREW HUBERMAN

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Drugs To Increase Dopamine Levels

  • Mucuna pruriens contain L-dopa which is the precursor for dopamine– but the crash takes place
  • L-tyrosine is an amino acid precursor to L-dopa; leads to a increase in dopamine and can improve focus but dosing is difficult to dial in and will be follow...

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Modulating Dopamine Levels (2)

  • Cold water exposure can boost dopamine up to 2.5x above baseline – but is sustained for up to three hours post-exposure
  • Dopamine controls the perception of time: when we engage in activity for the sole purpose of reward, time will feel longer because we are not relea...

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ANDREW HUBERMAN

Layering together multiple substances & activities that lead to big increases in dopamine can create pretty severe issues with motivation and energy right after those experiences

ANDREW HUBERMAN

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Levels Of Dopamine Increase By Activity

  • Chocolate - 1.5x increase above baseline
  • Sex (pursuit and act) - 2x baseline
  • Nicotine (when smoked) - 2.5x baseline
  • Cocaine - 2.5x baseline
  • Amphetamine - 10x baseline
  • ...

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