Unhappiness and depression are on the same platform. They both are caused due to our disconnection from what makes us happy.
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Depression is caused by the lack of what we need to be happy:
If the work you're doing isn't meaningful, people are bound to get anxious, depressed and unhappy. The most stress-inducing is the work that is monotonous and boring.
To be happy, we need to have meaningful values:
All of these are myths that give off the precedent that this is what happiness should be but it is mostly consumed by denial, detractory, and envy. Being able to accept the good with the bad will aid us into finding ourselves and explore what happiness truly means for us.
Attributing depression to spontaneously low serotonin is "deeply misleading and unscientific".
According to Dr. David Healy, there was never any basis for it, ever. It was just a marketing copy.