DXM and Kratom compete for the same metabolic pathway and will therefore interact when used together. Chemically speaking, DXM is an opioid, but it does not act on the body’s opiate receptors. Kratom, on the other hand, isn’t an opioid, and yet it interacts meaningfully with the opioid receptors in the central nervous system.
In terms of their effects, kratom and DXM are neutral to each other.
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