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The Molecule of More

The Molecule of More

by Daniel Z. Lieberman

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In the beginning, Dopamine was perceived as the "pleasure molecule".

Participants in early researches had pleasure when Dopamine was activated.

Reputation was consolidated through more research on drug addicts, and it was named the reward circuit. 

Later, it was discovered that ...

Most dopamine neurons signal a reward prediction error; they are activated by more reward than predicted (positive prediction error), remain at baseline activity for fully expected rewards, and show depressed activity with less reward than predicted (negative prediction).

When everything i...

Drugs reroute the dopamine circuit with a more intense stimulation than natural rewards as food or sex.

Different addictions are very similar because it hijacks the mechanism to keep us alive. 

People who love fine arts and those attracted by science have more in common because Dopamine controls both.

There is no significant difference between the poet and the physicist because both thrive in the abstract world, and Dopamine is about the future and imagination.

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You are probably very aware that the hard activities bring value to your life, and the others just momentary pleasure, so why do you still gravitate towards them? To understand this, we need to look at a neurotransmitter known as dopamine.

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