Hypersensitivity Reactions - Types - T cell - TeachMePhysiology
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Familiarising with allergic reactions-
Hypersensitivity reactions are an overreaction of the immune system to an antigen which would not normally trigger an immune response. The antigen may be something which would in most people be ignored – peanuts, for example, or it may originate from the body. In either case, the damage and clinical symptoms result from the body’s response to the substance rather than damage caused by the substance itself.
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Allergic reactions has genetic link-
The vulnerability of an individual to these reactions can have a genetic link. Overreaction to innocuous antigens are linked to changes in the CD regions of T-helper cell membranes, explaining why reactions like peanut allergies can commonly run in families. Overreaction to self-antigens is normally due to a failure in central tolerance, and this failure can also have genetically-inheritable features.
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