From an evolutionary perspective, we only live as long as we need to replace ourselves efficiently. For example:<ul><li>Mice live 2-3 years. They divert most of their resources into reproducing rapidly and little into preserving their bodies.</li><li>Whales live hundreds of years because they're at the top of the food chain and they can live as long as they want. So they breed slowly and build a body that lasts.</li><li>We, as humans, are somewhere in between mice and whales.</li></ul>From a biological perspective, there's no maximum to human lifespan. There's nothing that says biological organisms have to die.

Aging

Do what works for you and what you enjoy. What's a long life if it's not enjoyable?

Get into a constant sleep-wake cycle.Results from studies on people who work shifts show that disrupting your sleep-wake cycle accelerates aging and increases your risk of developing certain age-related diseases.

Sleep

It's been proven that exercise extends lifespan. People who exercise regularly have lower risk of major diseases such as heart disease.A basic routine with aerobic and strength training, done a few times a week, is enough. The main goal is for the aerobic training to reduce your heart disease risk, and for the strength training to maintain your hormone levels.However, bear in mind there are diminishing returns to exercise. Over-exercising is detrimental to your health as you wear out your joints.

Exercise

<ul><li>Diet: Eat healthy food. Don't overeat. Don't become obese</li><li>Exercise: Do aerobic and strength training a few times a week</li><li>Sleep: Get into a constant sleep-wake cycle</li><li>Manage your mental stress</li><li>Don't smoke because it accelerates aging</li></ul>

Tips to slow down aging

<ul><li>Eat a moderate amount of calories and eat during a shorter period during the day. You can do this through intermittent fasting and calorie restriction.</li><li>Eat plenty of leafy greens, such as broccoli, spinach, kale, or Brussels sprouts.</li><li>Reduce fruits that give you a sugar high because spiking your sugar is unhealthy in the long run. High sugar fruits include grapes, cherries, pears, watermelon, and bananas.</li><li>Limit your servings of red meat.</li></ul>

Diet

<ul><li>Fasting is one of oldest ways to improve health. We know it works, but we don't know why. Current research is aimed at figuring out what's optimal and how it works.</li><li>It's been shown that fasting activates some longevity genes, but the research is ongoing, so no recommendations can be made to the general public yet.</li><li>Results from animal studies show it's more important when you eat than what you eat. Mice that ate general food once a day lived longer than mice that ate carefully chosen food 3 times a day. But you want to focus on both — eat good food at the right time.</li></ul>

Research on fasting

What is the best way to live longer? Here are a few factors within your control

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Longevity

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Food

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How To Live A Long Life

TIL diseases show up more often in older people because of aging. It's causation, not correlation 🤯 So if we slow down aging, we decrease the risk for many age-related diseases

David Sinclair is a geneticist at Harvard and author of Lifespan. Please support this podcast by checking out our sponsors: - Onnit: https://lexfridman.com/onnit to get up to 10% off - Clear: https://clearme.com/lexpod and use code LexPod to get 2 months free - National Instruments (NI): https://www.ni.com/perspectives - SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera - Linode: https://linode.com/lex to get $100 free credit EPISODE LINKS: David's Twitter: https://twitter.com/davidasinclair David's Website: https://lifespanbook.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41 OUTLINE: 0:00 - Introduction 1:34 - Staying young at heart 5:30 - Bringing people back to life 11:05 - Wearables and tracking health data 20:18 - How to solve aging 30:22 - Why do we age? 35:50 - Genetic reset switch that reverses aging 38:20 - AI in biology 40:52 - Health data 48:58 - Fasting 56:29 - Diet 1:04:40 - Exercise 1:10:01 - Sleep 1:18:29 - Data 1:24:00 - Extending lifespan 1:26:42 - Immortality 1:32:28 - Denial of death 1:35:45 - Meaning of life without death SOCIAL: - Twitter: https://twitter.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - Medium: https://medium.com/@lexfridman - Reddit: https://reddit.com/r/lexfridman - Support on Patreon: https://www.patreon.com/lexfridman

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David Sinclair is a geneticist at Harvard and author of Lifespan. Please support this podcast by checking out our sponsors:
- Onnit: https://lexfridman.com/onnit to get up to 10% off
- Clear: https://clearme.com/lexpod and use code LexPod to get 2 months free
- National Instruments (NI): https://www.ni.com/perspectives
- SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera
- Linode: https://linode.com/lex to get $100 free credit

EPISODE LINKS:
David's Twitter: https://twitter.com/davidasinclair
David's Website: https://lifespanbook.com

PODCAST INFO:
Podcast website: https://lexfridman.com/podcast
Apple Podcasts: https://apple.co/2lwqZIr
Spotify: https://spoti.fi/2nEwCF8
RSS: https://lexfridman.com/feed/podcast/
Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4
Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41

OUTLINE:
0:00 - Introduction
1:34 - Staying young at heart
5:30 - Bringing people back to life
11:05 - Wearables and tracking health data
20:18 - How to solve aging
30:22 - Why do we age?
35:50 - Genetic reset switch that reverses aging
38:20 - AI in biology
40:52 - Health data
48:58 - Fasting
56:29 - Diet
1:04:40 - Exercise
1:10:01 - Sleep
1:18:29 - Data
1:24:00 - Extending lifespan
1:26:42 - Immortality
1:32:28 - Denial of death
1:35:45 - Meaning of life without death

SOCIAL:
- Twitter: https://twitter.com/lexfridman
- LinkedIn: https://www.linkedin.com/in/lexfridman
- Facebook: https://www.facebook.com/lexfridman
- Instagram: https://www.instagram.com/lexfridman
- Medium: https://medium.com/@lexfridman
- Reddit: https://reddit.com/r/lexfridman
- Support on Patreon: https://www.patreon.com/lexfridman

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