Specialist thrives in areas where:-

1. experience generates expertise in the field
2. pattern are repetitive, and pattern recognition is primary 
3. focus is the key component
4. during learning feedback to any action is fast and accurate.
5. situations are less dynamic and 
6. less no. of variable came in play

Eg of such areas are surgeon, chess player, golf etc

Generalist survives in areas :-

1. which are completely dynamic
2. where patterns rarely emerges
3. where situation are influenced by multiple variables.

In such area learning by repetition or deliberate practice is not fruitful as no feedback is possible and situations are continuously changing

Eg, Finance, Politics, International Relations, Economy etc

Specialist usually suffer from "cognitive entrenchment", however generalist have a range where they flexibly applies knowledge/training  from one area to other pursuits.

Generalist are generally open to new ideas and breadth of experience.

Generalist knew when to quit an unsuccessful endeavor without feeling guilty about it and experiment with something knew.

Biologically we do stay same , so our life and work preference changes overtime. Our personality changes with time &  experiences.

Hence, like Michelangelo we should not be afraid to try new things, as it is only way we can learn who we are and survive in this ever changing world.