A lot of the symptoms associated with a hangover are a product of sleep deprivation.
Alcohol affects our ability to get into what is known as rapid eye movement (REM) sleep, the bulk of which occurs in the last two-thirds of the night. As a rule of thumb, it takes about an hour to metabolize one unit of alcohol, so if you have a 250ml glass of wine at 7 pm it will mostly be out of your system by 10.30pm.
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