The Gut, the Heart, and TMAO - Cleveland HeartLab, Inc. - Deepstash
The Gut, the Heart, and TMAO - Cleveland HeartLab, Inc.

The Gut, the Heart, and TMAO - Cleveland HeartLab, Inc.

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The Gut, the Heart, and TMAO - Cleveland HeartLab, Inc.

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Another reason to reduce meat consumption

When you eat meat, your gut microbiome produces a chemical, trimethylene N-oxide (TMAO), which may raise your risk of getting cardiovascular events, like stroke and heart attack.  

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Mechanism of action

Eating foods high in choline and L-carnitine, your gut microbiome produce a chemical compound, called trimethylamine (TMA). In the liver, TMA is converted to trimethylene N-oxide (TMAO), a harmful agent. 

People with high blood levels of TMAO is shown to have higher risk of premature death. In addition, they have four-fold increased risk of all-cause death. 

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How to reduce TMAO in your body?

Reduce foods that is high in L-carnitine, choline and choline-containing compounds.

These are:

  • full-fat dairy products
  • egg yolk
  • cream cheese
  • butter
  • processed and unprocessed red meat
  • energy drinks and supplements that contain choline, lecithin (a choline-containing compound) and L-carnitine. 

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