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What Is the Human Microbiome, Exactly?

http://nautil.us/blog/what-is-the-human-microbiome-exactly

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What Is the Human Microbiome, Exactly?
Microbiome metaphors influence scientific understanding and can shape medical treatment.Illustration by vrx / ShutterstockAre you…

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The human microbiome

The human microbiome

The human body is made up of trillions of human cells. There are possibly three times as many microorganisms (bacteria, fungi, and other microbes) living in and on the human body. The microbial communities in and on the human body are known as the human microbiome.

The microbiome contributes considerably to human growth, development, and function. The most well known is the gut microbiome, which impacts human digestive health.

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Using metaphors to describe microbiomes

Metaphors that scientists use to talk about the microbiome influence scientific understanding and can shape medical treatment. For example, viewing the microbiome as an "organ" or a "part of the immune system."

Some physicians support fecal microbiota transplantation (FMT) - treating the malfunction of the gut microbiome by swallowing a pill full of someone else's poo. It follows the same basic principles as an organ transplant, and the treatment is probably a consequence of understanding the microbiome as an organ.

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A limited perspective on the human microbiome

To think of a microbiome as an organ creates a limited perspective because organs are relatively set. Generally, a heart will develop and remain the same in each person. But a microbiome is not one thing. It's trillions of things and responds to small changes in our diet, environment, and behavior. It works together with the human body in a symbiotic relationship.

Each metaphor can only capture a part of what the microbiome is. We need all the metaphors to understand the complexity of the microbiome and its role in our bodies.

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